M. Iglarz: search on Z-Library

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1

Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension

Bellaye, Pierre-Simon, Yanagihara, Toyoshi, Granton, Elise, Sato, Seidai, Shimbori, Chiko, Upagupta, Chandak, Imani, Jewel, Hambly, Nathan, Ask, Kjetil, Gauldie, Jack, Iglarz, Marc, Kolb, Martin

Journal:

European Respiratory Journal

Year:

2018

Language:

english

File:

PDF, 3.58 MB

english, 2018

2

Pharmacology of Macitentan, an Orally Active Tissue-Targeting Dual Endothelin Receptor Antagonist

Iglarz, M., Binkert, C., Morrison, K., Fischli, W., Gatfield, J., Treiber, A., Weller, T., Bolli, M. H., Boss, C., Buchmann, S., Capeleto, B., Hess, P., Qiu, C., Clozel, M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

3

Étude comparative du statut d'acide ascorbique des patients atteints de sclérodermie,de phénomène de Raynaud primitif et des volontaires sains

K.P. Tiev, G. Le Moel, V. Neguin, M. Iglarz, F. Driss, A. El Khattabi, M. Baret, M. Ziani, G. Durand, J. Cabane

Journal:

La Revue de Médecine Interne

Year:

2002

File:

PDF, 1008 KB

2002

4

Mechanisms of ET-1-induced Endothelial Dysfunction

Iglarz, Marc, Clozel, Martine

Journal:

Journal of Cardiovascular Pharmacology

Year:

2007

Language:

english

File:

PDF, 352 KB

english, 2007

5

Effect of Peroxisome Proliferator-Activated Receptor-alpha and -gamma Activators on Vascular Remodeling in Endothelin-Dependent Hypertension

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2003

Language:

english

File:

PDF, 777 KB

english, 2003

6

Chronic endothelin-1-induced changes in vascular reactivity in rat resistance arteries and aorta

Marc Iglarz, Bernard I. Lévy, Daniel Henrion

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 223 KB

english, 1998

7

Renal, retinal and cardiac changes in type 2 diabetes are attenuated by macitentan, a dual endothelin receptor antagonist

S. Sen, S. Chen, B. Feng, M. Iglarz, S. Chakrabarti

Journal:

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

8

Position of Src tyrosine kinases in the interaction between angiotensin II and endothelin in in vivo vascular protein synthesis

Beaucage, Pierre, Iglarz, Marc, Servant, Marc, Touyz, Rhian M, Moreau, Pierre

Journal:

Journal of Hypertension

Year:

2005

Language:

english

File:

PDF, 618 KB

english, 2005

9

Involvement of Renin–Angiotensin System in Pressure–Flow Relationship

Lasocki, Sigismond, Iglarz, Marc, Seince, Pierre-François, Vuillaumier-Barrot, Sandrine, Vicaut, Eric, Henrion, Daniel, Levy, Bernard, Desmonts, Jean-Marie, Philip, Ivan, Bénessiano, Joelle

Journal:

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

10

Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice

Houde, Martin, Desbiens, Louisane, Schwertani, Adel, Pejler, Gunnar, Iglarz, Marc, D'Orléans-Juste, Pedro

Journal:

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

11

Role of endothelin-1 in hypertension

Marc Iglarz, Ernesto L. Schiffrin

Journal:

Current Hypertension Reports

Year:

2003

Language:

english

File:

PDF, 339 KB

english, 2003

12

Involvement of oxidative stress in the profibrotic action of aldosterone: Interaction with the renin-angiotensin system

Marc Iglarz, Rhian M. Touyz, Emilie C. Viel, Farhad Amiri, Ernesto L. Schiffrin

Journal:

American Journal of Hypertension

Year:

2004

Language:

english

File:

PDF, 324 KB

english, 2004

13

Identification of a Novel Role for Endothelins within the Oviduct

Jeoung, Myoungkun, Lee, Sungeun, Hawng, Hee-kyung, Cheon, Yong-Pil, Jeong, Youn Kyung, Gye, Myung Chan, Iglarz, Marc, Ko, CheMyong, Bridges, Phillip J.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

14

The deletion genotype of the angiotensin I-converting enzyme is associated with an increased vascular reactivity in vivo and in vitro

Daniel Henrion, Joelle Benessiano, Ivan Philip, Sandrine Vuillaumier-Barrot, Marc Iglarz, Gaetan Plantefève, Didier Chatel, Ulrich Hvass, Geneviève Durand, Jean-Marie Desmonts, Philippe Amouyel, Berna

Journal:

Journal of the American College of Cardiology

Year:

1999

Language:

english

File:

PDF, 190 KB

english, 1999

15

The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation

Steven, Sebastian, Oelze, Matthias, Hausding, Michael, Roohani, Siyer, Kashani, Fatemeh, Kröller-Schön, Swenja, Helmstädter, Johanna, Jansen, Thomas, Baum, Christine, Iglarz, Marc, Schulz, Eberhard, M

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2018

Language:

english

File:

PDF, 4.73 MB

english, 2018

16

Selective prostacyclin receptor agonist selexipag, in contrast to prostacyclin analogs, does not evoke paradoxical vasoconstriction of rat femoral artery

Morrison, Keith, Haag, Franck, Ernst, Roland, Iglarz, Marc, Clozel, Martine

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 652 KB

english, 2018

17

Endothelin-2 in Ovarian Follicle Rupture

Ko, CheMyong, Gieske, Mary C., Al-Alem, Linah, Hahn, YunKyung, Su, Wen, Gong, Ming C., Iglarz, Marc, Koo, Yongbum

Journal:

Year:

2006

Language:

english

File:

PDF, 1.37 MB

english, 2006

18

Chronic Blockade of Endothelin Receptors Improves Ischemia-Induced Angiogenesis in Rat Hindlimbs Through Activation of Vascular Endothelial Growth Factor-NO Pathway

Iglarz, M., Silvestre, J.-S., Duriez, M., Henrion, D., Levy, B. I.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2001

Language:

english

File:

PDF, 2.19 MB

english, 2001

19

Comparison of Macitentan and Bosentan on Right Ventricular Remodeling in a Rat Model of Non-vasoreactive Pulmonary Hypertension

Iglarz, Marc, Landskroner, Kyle, Bauer, Yasmina, Vercauteren, Magali, Rey, Markus, Renault, Berengère, Studer, Rolf, Vezzali, Enrico, Freti, Diego, Hadana, Hakim, Schläpfer, Manuela, Cattaneo, Christo

Journal:

Journal of Cardiovascular Pharmacology

Year:

2015

Language:

english

File:

PDF, 972 KB

english, 2015

20

Absence of ETA receptors on podocytes is not antialbuminuric in diabetic mice

Vignon-Zellweger, Nicolas, Heiden, Susi, Nakayama, Kazuhiko, Yagi, Keiko, Iglarz, Marc, Yanagisawa, Masashi, Emoto, Noriaki

Journal:

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

21

Comparison of pharmacological activity of macitentan and bosentan in preclinical models of systemic and pulmonary hypertension

Iglarz, Marc, Bossu, Alexandre, Wanner, Daniel, Bortolamiol, Céline, Rey, Markus, Hess, Patrick, Clozel, Martine

Journal:

Year:

2014

Language:

english

File:

PDF, 937 KB

english, 2014

22

Countervailing vascular effects of rosiglitazone in high cardiovascular risk mice: role of oxidative stress and PRMT-1

Savoia, Carmine, Ebrahimian, Talin, Lemarié, Catherine A., Paradis, Pierre, Iglarz, Marc, Amiri, Farhad, Javeshgani, Danesh, Schiffrin, Ernesto L.

Journal:

Clinical Science

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

23

Granulomatous lung inflammation is nanoparticle type-dependent

Pacheco, Yves, Ponchon, Marine, Lebecque, Serge, Calender, Alain, Bernaudin, Jean François, Valeyre, Dominique, Iglarz, Marc, Strasser, Daniel S., Studer, Rolf, Freti, Diego, Renno, Toufiq, Bentaher,

Journal:

Experimental Lung Research

Year:

2018

Language:

english

File:

PDF, 1.23 MB

english, 2018

24

CHRONIC DECREASE IN FLOW CONTRIBUTES TO HEART FAILURE-INDUCED ENDOTHELIAL DYSFUNCTION IN RATS

C Devaux, M Iglarz, V Richard, P Mulder, D Henrion, S Renet, JP Henry, C Thuillez

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2004

Language:

english

File:

PDF, 116 KB

english, 2004

25

EXPRESS: Selective Improvement of Pulmonary Arterial Hypertension with a Dual ET A /ET B Receptors Antagonist in the Apolipoprotein E -/- Model of PAH and Atherosclerosis

Renshall, Lewis James, Arnold, Nadine D, West, Laura, Braithwaite, Adam, Pickworth, Josephine Ann, Walker, Rachel, Alfaidi, Mabruka A, Casbolt, Helen, Thompson, A. A. Roger, Holt, Cathy, Iglarz, Marc,

Journal:

Pulmonary Circulation

Year:

2017

Language:

english

File:

PDF, 365 KB

english, 2017

26

Genetic determinants of vascular reactivity

Daniel Henrion, Joelle Benessiano, Marc Iglarz, Ivan Philip, Bernard I. Levy

Journal:

Current Hypertension Reports

Year:

2002

Language:

english

File:

PDF, 610 KB

english, 2002

27

Involvement of oxidative stress in the profibrotic action of aldosteroneInteraction with the renin-angiotensin system

IGLARZ, M, TOUYZ, R, VIEL, E, AMIRI, F, SCHIFFRIN, E

Journal:

American Journal of Hypertension

Year:

2004

Language:

english

File:

PDF, 324 KB

english, 2004

28

Chronic Endothelin-1 Improves Nitric Oxide Dependent Flow-Induced Dilation in Resistance Arteries From Normotensive and Hypertensive Rats

Henrion, D., Iglarz, M., Levy, B. I.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

1999

Language:

english

File:

PDF, 555 KB

english, 1999

29

Treatment of obesity and pulmonary arterial hypertension with inhibitors of the prostaglandin transporter: evaluation of patent WO2014/204895A1

Dingemanse, Jasper, Bolli, Martin, Iglarz, Marc

Journal:

Expert Opinion on Therapeutic Patents

Year:

2015

Language:

english

File:

PDF, 1.87 MB

english, 2015

30

Discovery of novel bridged tetrahydronaphthalene derivatives as potent T/L-type calcium channel blockers

Renneberg, Dorte, Hubler, Francis, Rey, Markus, Hess, Patrick, Delahaye, Stephane, Gatfield, John, Iglarz, Marc, Hilpert, Kurt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 633 KB

english, 2015

31

Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP

Pu, Qian, Brassard, Pascal, Javeshghani, Danesh M, Iglarz, Marc, Webb, Randy L, Amiri, Farhad, Schiffrin, Ernesto L

Journal:

Journal of Hypertension

Year:

2008

Language:

english

File:

PDF, 475 KB

english, 2008

32

Endothelin ET A Receptor Blockade, by Activating ET B Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention

Vercauteren, Magali, Trensz, Frederic, Pasquali, Anne, Cattaneo, Christophe, Strasser, Daniel S., Hess, Patrick, Iglarz, Marc, Clozel, Martine

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

33

Antiangiogenic Effect of Angiotensin II Type 2 Receptor in Ischemia-Induced Angiogenesis in Mice Hindlimb

Silvestre, Jean-Sébastien, Tamarat, Radia, Senbonmatsu, Takaaki, Icchiki, Toshihiro, Ebrahimian, Teni, Iglarz, Marc, Besnard, Sandrine, Duriez, Micheline, Inagami, Tadashi, Lévy, Bernard I.

Journal:

Circulation Research

Year:

2002

Language:

english

File:

PDF, 353 KB

english, 2002

34

Identification of a Novel Role for Endothelins within the Oviduct

Jeoung, Myoungkun, Lee, Sungeun, Hawng, Hee-kyung, Cheon, Yong-Pil, Jeong, Youn Kyung, Gye, Myung Chan, Iglarz, Marc, Ko, CheMyong, Bridges, Phillip J.

Journal:

Year:

2010

Language:

english

File:

PDF, 358 KB

english, 2010

35

At the heart of tissue: endothelin system and end-organ damage

Iglarz, Marc, Clozel, Martine

Journal:

Clinical Science

Year:

2010

Language:

english

File:

PDF, 255 KB

english, 2010

36

Chronic blockade of endothelin ETA receptors improves flow dependent dilation in resistance arteries of hypertensive rats

Iglarz, Marc, Matrougui, Khalid, Lévy, Bernard I., Henrion, Daniel

Journal:

Cardiovascular Research

Year:

1998

Language:

english

File:

PDF, 238 KB

english, 1998

37

Peroxisome Proliferator-Activated Receptors: Vascular and Cardiac Effects in Hypertension

Schiffrin, E. L., Amiri, F., Benkirane, K., Iglarz, M., Diep, Q. N.

Journal:

Year:

2003

Language:

english

File:

PDF, 359 KB

english, 2003

38

EXPRESS: Dual et a /et b blockade with macitentan improves both vascular remodelling and angiogenesis in pulmonary arterial hypertension

Nadeau, Valerie, Potus, Francois, BOUCHERAT, Olivier, Paradis, Renee, Tremblay, Eve, Iglarz, Marc, PAULIN, Roxane, Bonnet, Sebastien, PROVENCHER, Steeve

Journal:

Pulmonary Circulation

Year:

2017

Language:

english

File:

PDF, 2.02 MB

english, 2017

39

Preproendothelin-1 Gene Polymorphism Is Related to a Change in Vascular Reactivity in the Human Mammary Artery In Vitro

Iglarz, M., Benessiano, J., Philip, I., Vuillaumier-Barrot, S., Lasocki, S., Hvass, U., Durand, G., Desmonts, J.-M., Levy, B. I., Henrion, D.

Journal:

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

40

Peroxisome Proliferator-Activated Receptor- and Receptor- Activators Prevent Cardiac Fibrosis in Mineralocorticoid-Dependent Hypertension

Iglarz, M., Touyz, R. M., Viel, E. C., Paradis, P., Amiri, F., Diep, Q. N., Schiffrin, E. L.

Journal:

Year:

2003

Language:

english

File:

PDF, 451 KB

english, 2003

41

Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis

Kosanovic, Djuro, Luitel, Himal, Dahal, Bhola Kumar, Cornitescu, Teodora, Janssen, Wiebke, Danser, A.H. Jan, Garrelds, Ingrid M., De Mey, Jo G.R., Fazzi, Gregorio, Schiffers, Paul, Iglarz, Marc, Fisch

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 3.40 MB

english, 2015

42

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor- and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist

Cipriani, P., Di Benedetto, P., Ruscitti, P., Capece, D., Zazzeroni, F., Liakouli, V., Pantano, I., Berardicurti, O., Carubbi, F., Pecetti, G., Turricchia, S., Alesse, E., Iglarz, M., Giacomelli, R.

Journal:

The Journal of Rheumatology

Year:

2015

Language:

english

File:

PDF, 3.58 MB

english, 2015

43

Lucerastat, an iminosugar for substrate reduction therapy in Fabry disease: preclinical evidence

Welford, Richard W.D., Mühlemann, Andreas, Priestman, David, Garzotti, Marco, Deymier, Caroline, Ertel, Eric A, Iglarz, Marc, Baldoni, Daniela, Platt, Frances M., Probst, Markus R.

Journal:

Molecular Genetics and Metabolism

Year:

2017

Language:

english

File:

PDF, 63 KB

english, 2017

44

Determination of 2-n-propylquinoline in mouse plasma and liver by high-performance liquid chromatography

M Iglarz, B Baune, J.C Gantier, R Hocquemiller, R Farinotti

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 85 KB

english, 1998

45

Endothelin-2 induces oviductal contraction via endothelin receptor subtype A in rats

Al-Alem, L., Bridges, P. J, Su, W., Gong, M. C, Iglarz, M., Ko, C.

Journal:

Journal of Endocrinology

Year:

2007

Language:

english

File:

PDF, 386 KB

english, 2007

46

Eplerenone Prevents Salt-Induced Vascular Remodeling and Cardiac Fibrosis in Stroke-Prone Spontaneously Hypertensive Rats

Endemann, D. H., Touyz, R. M., Iglarz, M., Savoia, C., Schiffrin, E. L.

Journal:

Year:

2004

Language:

english

File:

PDF, 368 KB

english, 2004

47

Improved metabolic syndrome-related right and left ventricular dysfunction by the dual ET A -ET B receptor antagonist macitentan

Lachaux, M., Harouki, N., Peschanski, N., Nicol, L., Dumesnil, A., Henry, J.P., Renet, S., Jouet, I., Iglarz, M., Richard, V., Mulder, P.

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2017

Language:

english

File:

PDF, 69 KB

english, 2017

48

Synergistic vascular protective effects of combined low doses of PPARα and PPARγ activators in angiotensin II-induced hypertension in rats

C De Ciuceis, F Amiri, M Iglarz, J S Cohn, R M Touyz, E L Schiffrin

Journal:

British Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 177 KB

english, 2007

49

The Discovery of N -[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]- N ′-propylsulfamide (Macitentan), an Orally Active, Potent Dual Endothelin Receptor Antagonist

Bolli, Martin H., Boss, Christoph, Binkert, Christoph, Buchmann, Stephan, Bur, Daniel, Hess, Patrick, Iglarz, Marc, Meyer, Solange, Rein, Josiane, Rey, Markus, Treiber, Alexander, Clozel, Martine, Fis

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 607 KB

english, 2012

50

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] D36. ANIMAL MODELS OF PULMONARY FIBROSIS - Optimization Of Tissue Targeting Properties Of Macitentan, A New Dual Endothelin Receptor Antagonist, Improves Its Efficacy In A Rat Model Of Pulmonary Fibrosis Associated With Pulmonary Arterial Hypertension

Iglarz, Marc, Landskroner, Kyle, Rey, Markus, Wanner, Daniel, Hess, Patrick, Clozel, Martine

Year:

2011

Language:

english

File:

PDF, 19 KB

english, 2011

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